The response surface methodology (RSM) was used to optimize NaClO leaching process of gold from the refractory gold ores in Guizhou, and the interaction among four factors, namely, NaClO concentration, temperature, liquid-solid ratio and pH, and their effects on the gold leaching rate were investigated, and the parameters were optimized. RSM analysis showed that the significant order of each factor on the gold leaching rate was NaClO concentration > liquid-solid ratio > pH > temperature, and the interaction between NaClO concentration and pH was more significant. A good gold leaching rate of 93.4% were achieved under the condition as follows: a reaction time of 3 h, NaClO concentration of 0.9 mol/L, pH=13.4, liquid-solid ratio of 8.2, and temperature of 27 ℃. |